
产品货号:
Z10403
中文名称:
ACVR1抗体
英文名称:
Anti-ACVR1 Antibody
产品规格:
0.1mg
发货周期:
1~3天
产品价格:
询价
抗体名称 | Anti-ACVR1 Antibody |
指标别名 | activin A receptor;type I;Activin receptor like kinase 2;Activin receptor type 1;Activin receptor type I;ACTR I;ACTRI;ACVR1;ACVR1A;ACVRLK2;ALK 2;ALK2;FOP;SKR1;TSR I;TSRI |
克隆性 | Polyclonal |
检验物种 | human,mouse |
应用范围 | ELISA,WB |
基因名称 | ACVR1 |
抗体来源 | Rabbit |
抗体类型 | IgG |
免疫原 | ACVR1 antibody was raised against a 14 amino acid synthetic peptide near the amino terminus of the human ACVR1.The immunogen is located within the first 50 amino acids of ACVR1. |
计算分子量 | 57kDa |
成分 | ACVR1 Antibody is supplied in PBS containing 0.02% sodium azide. |
纯化方式 | ACVR1 Antibody is affinity chromatography purified via peptide column. |
浓度 | 1mg/mL |
产品形态 | 溶液 |
保存条件 | 4℃可保存3个月,-20℃可保存1年。 |
背景资料 | Activins are dimeric growth and differentiation factors which belong to the transforming growth factor-beta (TGF-beta) superfamily of structurally related signaling proteins.Activins signal through a heteromeric complex of receptor serine kinases which include at least two type I and two type II receptors.Unlike ACVR1B and ACVR1C,ACVR1,also known as activin receptor-like kinase 2 (ALK2),can not transduce activin-mediated signaling,but will transduce BMP and Mullerian inhibiting substance (MIS) group signaling.It is thought that ACVR1 also inhibits activin signaling by blocking the binding of activin to its type II receptor.Recent studies indicate that genetic variation in ACVR1 is associated with polycystic ovary syndrome,suggesting that ACVR1 signaling contributes to disturbed folliculogenesis in these patients. |
Uniprot ID | Q04771 |
基因名全称 | Activin A receptor,type I |
蛋白名全称 | Activin A receptor,type I |
推荐稀释比 | ACVR1 antibody can be used for detection of ACVR1 by Western blot at 1μg/mL.Antibody validated:Western Blot in human samples.All other applications and species not yet tested. |
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